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Focus shifts for a fascinating Premier League matchup as league leaders Arsenal entertain rock-bottom Wolves to the their home ground.

Starting Lineups

Mikel Arteta's side have opted for a trio of alterations from the side that endured a 2-1 defeat at Villa Park last weekend. William Saliba, Viktor Gyökeres and Gabriel Martinelli all come into the lineup. Martin Ødegaard and the Spanish midfielder drop to the bench, while Riccardo Calafiori is not involved. The centre-back is back after missing five matches through injury.

Wolves also make three adjustments to their starting XI following being soundly beaten 4-1 at Molineux by United on Monday evening. Matt Doherty, João Gomes and the South Korean forward come in. Ki-Jana Hoever and Jhon Arias drop to the substitutes, while Jean‐Ricner Bellegarde is not in the squad altogether.

Confirmed Lineups

Arsenal: Raya, White, Saliba, Hincapie, Timber, Eze, Zubimendi, Rice, Saka, Gyokeres, Martinelli.
Bench: Arrizabalaga, Odegaard, Gabriel Jesus, Norgaard, Trossard, Madueke, Nwaneri, Merino, Lewis-Skelly.

Wolverhampton Wanderers: Johnstone, Mosquera, Agbadou, Toti Gomes, Doherty, Joao Gomes, Andre Trindade, Krejci, Wolfe, Larsen, Hwang.
Substitutes: Tchatchoua, Mane, Lopez, Hoever, Chirewa, Arokodare, Arias, Santiago Bueno, Jose Sa.

Referee: Robert Jones
VAR Official: John Brooks

The Setup

Good evening! And I mean, look at this …

The standings tells a striking story. Arsenal sit comfortably at the pinnacle of the Premier League, while Wolves prop up the league.

… however, even though this will be the 42nd time the top side have played the side at the foot of the entire table – with 30 victories from 41, with seven tied games – who are responsible for two of the four historical shocks? Why, Wolverhampton Wanderers, of course! So while Mikel Arteta will undoubtedly be expecting another three points, Rob Edwards must know that long shots occasionally come off, and you never know. The start is at 8 o'clock in the evening GMT. Let's go!

^{(The remaining last-over-first wins in the modern top-flight era are Oldham Athletic's 1-0 win over United in March 1993, and Tottenham Hotspur – yeah, this one sounds a bit weird - defeating Liverpool in November 2008.)}